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Epigenetic changes may explain chronic kidney disease 2013-12-03

By Perelman School of Medicine at the University of Pennsylvania

Researchers found, in a genome-wide survey, significant differences in the pattern of chemical modifications on DNA that affect gene expression in kidney cells from patients with chronic kidney disease versus healthy controls. This is the first study to s

Scientists capture 'redox moments' in living cells 2013-12-03

By Pacific Northwest National Laboratory

Scientists have glimpsed key chemical events, known as redox reactions, inside living cells of fast-growing Synechococcus. The work marks the first time that redox activity has been observed in specific proteins within living cells.

Continued increases in adhd diagnoses, treatment with meds among US children 2013-12-03

By Elsevier

New study reports that half of U.S. children diagnosed with ADHD received that diagnosis by age 6. The study found that an estimated two million more children in the United States (U.S.) have been diagnosed with attention-deficit/hyperactivity disorder (A

Update: 50 percent of patients in new brain cancer study alive after five years 2013-12-03

By Cedars-Sinai Medical Center

Eight of 16 patients participating in a study of an experimental immune system therapy directed against the most aggressive malignant brain tumors – glioblastoma multiforme – survived longer than five years after diagnosis, according t

New framework for neglected tropical diseases could help world's poorest people 2013-12-03

By Sabin Vaccine Institute

A new concept and policy framework urges G20 countries to lead on making greater investments in neglected tropical diseases in light of new era in global health and development.

Oatmeal beats ready-to-eat breakfast cereal at improving appetite control 2013-12-03

By Taylor & Francis

While obesity is a complex and multifaceted problem, much of the strategy behind combating it boils down to healthy eating habits. Taking into account the primary role of subjective appetite sensations in said habits, a group of researchers recently compa

Human neural stem cells could address critical limb ischemia 2013-12-03

By University of Bristol

New research has shown human neural stem cells could improve blood flow in critical limb ischemia through the growth of new vessels.

Powerful tool for genetic engineering 2013-12-03

By Helmholtz Centre for Infection Research

Viruses cannot only cause illnesses in humans, they also infect bacteria. Those protect themselves with a kind of "immune system" which -- simply put -- consists of specific sequences in the genetic material of the bacteria and a suitable enzyme

Study identifies protein essential for immune recognition, response to viral infection 2013-12-03

By Massachusetts General Hospital

A research team has identified an immune cell protein that is critical to setting off the body's initial response against viral infection. They found that a protein called GEF-H1 is essential to the ability of macrophages -- major contributors to the inna

Lessons learned about influenza A, four years after epidemic 2013-12-03

By Elhuyar Fundazioa

With autumn upon us, and a new flu strain lying in wait, the presentation of a study analyzing the management of the 2009 influenza A crisis could not, if anything, be better timed. A pediatrician offers insight into her analysis of how the H1N1 virus aff

Chemotherapy: When intestinal bacteria provide reinforcement 2013-12-03

By INSERM (Institut national de la santé et de la recherche médicale)

Research has led to a rather surprising discovery on the manner in which cancer chemotherapy treatments act more effectively with the help of the intestinal flora (also known as the intestinal microbiota).

Potential new treatments for acute myeloid leukemia 2013-12-03

By National University of Singapore

In two separate studies on CEBPA mutations in acute myeloid leukemia (AML) subtypes, researchers successfully identified and validated a gene known as Sox4 as a potential therapeutic target and a class of anti-cancer drugs, histone deacetylase inhibitors,

PCBs still affecting health decades later 2013-12-03

By Universite de Montreal

Although PCBs have been banned in the United States since 1979, a researcher has found that higher levels of the toxin was associated with lower cognitive performance in seniors.

Antidepressant medication does not increase risk of autism 2013-12-03

By Aarhus University

A large Danish study shows that pregnant women's use of antidepressant medication does not increase the risk of having children with autism. In this way the study refutes earlier studies, which had demonstrated a connection.

Stuck on flu 2013-12-03

By University of California, San Diego Health Sciences

Researchers have shown for the first time how influenza A viruses snip through a protective mucus net to both infect respiratory cells and later cut their way out to infect other cells.

Why some ear, respiratory infections become chronic 2013-12-03

By Nationwide Children's Hospital

Scientists have figured out how a bacterium that causes ear and respiratory illnesses is able to elude immune detection in the middle ear, likely contributing to chronic or recurrent infections in adults and children.

Marijuana's potential for treating autoimmune disorders 2013-12-03

By University of South Carolina

A new study provides evidence that THC (tetrahydrocannabinol), a principal ingredient in marijuana, may be beneficial in treating those with autoimmune disorders. The study is the first to explore how tiny, yet powerful molecules called microRNAs are infl

Gene-silencing study finds new targets for Parkinson's disease 2013-12-03

By NIH/National Institute of Neurological Disorders and Stroke

Scientists have used RNA interference technology to reveal dozens of genes that may represent new therapeutic targets for treating Parkinson's disease. The findings also may be relevant to several diseases caused by damage to mitochondria, the biological

Sugar-sweetened beverage consumption increases endometrial cancer risk 2013-12-03

By American Association for Cancer Research (AACR)

Postmenopausal women who consumed sugar-sweetened beverages were more likely to develop the most common type of endometrial cancer compared with women who did not drink sugar-sweetened beverages, according to a study published.

Dysfunctional mitochondria may underlie resistance to radiation therapy 2013-12-03

By University of Illinois at Chicago

The resistance of some cancers to the cell-killing effects of radiation therapy may be due to abnormalities in the mitochondria -- the cellular structures responsible for generating energy, according to an international team of researchers.

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