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Staying ahead of Huntington's disease 2013-12-18

By Washington University in St. Louis

Researchers have made strides in staying ahead of Huntington’s disease, a devastating, incurable disorder that results from the death of certain neurons in the brain.

Immune cells outside brain may regulate vulnerability to depression 2013-12-18

By American College of Neuropsychopharmacology

A new study shows that immune cells outside the brain may regulate propensity to develop depression. Depression is a chronic disorder with a devastating impact on the quality of life, health and life expectancy of those who suffer from the disorder. The u

Older mice fed wolfberries show reduced risk for flu virus with vaccine 2013-12-18

By Tufts University

In a study of older mice, wolfberries appear to interact with the influenza vaccine to offer additional protection against the flu virus. The research suggests the wolfberry may increase the activity of dendritic cells, which play an important role in the

Systems medicine paves way for improved treatment for leukemia patients 2013-12-18

By Helsingin yliopisto (University of Helsinki)

A new individualized systems medicine strategy enables a selection of potentially effective cancer therapies for individual patients. These are promising results achieved by applying this strategy to chemoresistant adult acute myeloid leukemia patients.

Scientists resolve decades-old mystery of ‘chlamydial anomaly’ 2013-12-18

By Uniformed Services University of the Health Sciences (USU)

A 50-year-old mystery surrounding the existence of a cell wall in the bacterial pathogen Chlamydia trachomatis, or chlamydia, has been solved. Chlamydia is the leading cause of sexually transmitted infections worldwide, infecting nearly 1.5 million Americ

Ceratin gene mutations make breast cancers treatment-resistant 2013-12-18

By American Association for Cancer Research

Women with breast cancer characterized by high levels of the protein HER2 and hormone receptors gained much less benefit from presurgery treatment with chemotherapy and HER2-targeted therapies if their cancer had one or more mutations in the PIK3CA gene,

More powerful approach to analyze melanoma's genetic causes 2013-12-18

By The Geisel School of Medicine at Dartmouth

There may be a better way to analyze the genetic causes of cutaneous melanoma according to a study published. A statistical analysis using the natural and orthogonal interaction model showed increased power over existing approaches for detecting genetic e

High levels of maternal care has life-long impact on vulnerability to stress, study says 2013-12-18

By American College of Neuropsychopharmacology

A new study shows that high levels of maternal care during the early post-natal period in rodents can reduce the sensitivity of the offspring to stressful events during adulthood. Maternal care is shown to chemically modify and thereby re-program genes th

Combining mutants results in 5-fold lifespan extension in C. elegans 2013-12-18

By Buck Institute for Age Research

What are the limits to longevity? Scientists combined mutations in two pathways well-known for lifespan extension and report a synergistic five-fold lifespan extension in the nematode C. elegans. The worms lived to the human equivalent of 400 to 500 years

Asia Pacific must prepare for catastrophic increase in fragility fractures 2013-12-18

By International Osteoporosis Foundation

A new report shows that osteoporosis is a serious problem throughout the Asia Pacific, with the number of fracture sufferers to rise dramatically in the coming decades. The report provides new and updated information and data about the status and epidemio

Effects of migrations, 'closed holdings' on DNA of Alpine peoples 2013-12-18

By European Academy of Bozen/Bolzano

A genetic study sheds light on the history of the populations, indicating that the genetic make-up of human beings is a result of their biological evolution, which is also influenced by geographical and socio-cultural factors such as environmental feature

Antihormone therapy anastrozole may provide new option for breast cancer prevention 2013-12-18

By American Association for Cancer Research

Breast cancer incidence among postmenopausal women at high risk for developing the disease was significantly reduced by the antihormone therapy anastrozole, indicating that the drug may be an effective new option for breast cancer prevention for this grou

For altitude training, a narrow window for success 2013-12-18

By American Physiological Society

In a new study, researchers found that living between 2,000 and 2,500 meters above sea level offered the best performance enhancement compared to living at higher or lower elevations. These findings could help competitive endurance athletes and their coac

Nonconcussion head impacts in contact sports linked to brain changes and lower test scores 2013-12-18

By Indiana University

Repeated blows to the head during a season of contact sports may cause changes in the brain's white matter and affect cognitive abilities even if none of the impacts resulted in a concussion.

Dietary amino acids improve sleep problems in mice with traumatic brain injury 2013-12-18

By Oregon Health & Science University

Scientists have discovered how to fix sleep disturbances in mice with traumatic brain injuries -- a discovery that could lead to help for hundreds of thousands of people who have long-term and debilitating sleep and wakefulness issues after they suffer co

Increased survival for metastatic prostate cancer with chemotherapy, hormone therapy together 2013-12-18

By National Cancer Institute (NCI) at NIH

Men with hormone-sensitive metastatic prostate cancer who received the chemotherapy drug docetaxel given at the start of standard hormone therapy lived longer than patients who received hormone therapy alone, according to early results from a National Ins

Rare gene variants double risk for Alzheimer's disease 2013-12-18

By Washington University in St. Louis

A team of researchers has identified variations in a gene that double a person’s risk of developing Alzheimer’s disease later in life. The newly identified variations occur rarely in the population, making them hard for researchers to

Diabetes drugs affect hearts of men, women differently 2013-12-18

By Washington University School of Medicine

Widely used treatments for type 2 diabetes have different effects on the hearts of men and women, even as the drugs control blood sugar equally well in both sexes, according to researchers. The investigators used PET scans to measure heart and whole-body

Study finds that pediatric obesity patients like telehealth services 2013-12-18

By University of California, Los Angeles (UCLA), Health Sciences

A pilot program offering telehealth technology to pediatric obesity patients found that a great majority of pediatric patients were satisfied with their telehealth appointment.

First test to predict acute mountain sickness 2013-12-18

By European Society of Cardiology

The first test to identify acute mountain sickness has been developed by a team of researchers in Italy and France. The test could revolutionize trekking and climbing by predicting who will develop the potentially deadly condition so they can avoid high a

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