Taking Viagra halves the risk of men who suffer from type 2 diabetes dying from heart problems 2016-11-12
Taking a Viagra pill every few months almost halves the risk of men with type 2 diabetes dying with heart problems, research suggests.
The study of 6,000 British men could pave the way for erectile dysfunction pills to be prescribed regularly for men with diabetes.
Nearly four million people in the UK suffer with type 2 diabetes, and 12million more are at risk of developing the disease.
People with the condition are at twice the risk of others of developing heart disease.
This is partly because the hearts of diabetics become less efficient over time, unable to contract properly and pump blood all around the body.
Experts think Viagra, and other similar erectile dysfunction drugs, improve this function. The drug, which has earned pharmaceutical firms more than £1billion a year since it was launched as an erectile drug in 1998, works by relaxing blood vessels, improving blood flow to the groin.
This function also affects the ability of the heart to pump blood, scientists think.
The team studied the health records of 5,956 men with type 2 diabetes, aged between 40 and 89. Of that group, 1,359 took erectile dysfunction drugs called PDE5 inhibitors – of which Viagra is one form.
They took the drugs only an average of 16 times over the seven-year study period – less than once every five months.
But they were 46 per cent less likely to die of heart disease during the study period, the scientists found.
Patients taking the drugs were also 38 per cent less likely to suffer a heart attack – and those who did were 40 per cent less likely to die as a result.
The scientists, whose results are published in the BMJ journal Heart, adjusted the figures for age, blood pressure, prior heart problems and other medication use. Professor Andrew Trafford, of Manchester University, one of the scientists, said: ‘Diabetes is a major risk factor for heart disease so treatments that could reduce that risk are urgently needed.
‘Erectile dysfunction treatments like Viagra are already licensed for use so, if trials provide further evidence of a life-saving benefit, it might be possible to start treating people with this drug in the not too distant future.’
He stressed that Viagra would not work for all male heart patients, but if further trials confirm his results, he expects that it could be prescribed for many diabetics. It is not licensed for use by women, but in theory it might help female diabetics, although further trials would be needed to show it is safe for them.
Professor Jeremy Pearson, of the British Heart Foundation, which funded the research, said: ‘Viagra was originally being developed as a cardiovascular treatment in the UK.
‘Researchers were looking at its use in people with high blood pressure and angina… so it’s promising to see we may have rediscovered its potential in fighting heart disease.’